To date, our work on the American Growth Project has focused on the United States’ most populous urban areas. Our previous analyses of growth and productivity in the 50 largest Extended Metropolitan Areas (EMAs) have served to illustrate the tremendous amount of economic diversity to be found within the United States, revealing stark variations in economic trends, major industries and migration patterns in the country’s largest cities. Taken together, these findings have reinforced our view that national statistics alone fail to account for the underlying drivers of economic expansion and contraction – and thus tell an incomplete story of the country’s economic health. With that in mind, we turn now to the task of measuring and analyzing economic activity in the next largest set of EMAs: the top 100 midsize cities.